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Holmes led the efforts that resulted in the first ever clinical candidate of a genome editing-based therapy and has extensive experience in the genome editing of T-cells, hematopoietic stem cells, and hepatocytes. Holmes was the Chief Scientific Officer of Ambys Medicines, and he also held various leadership positions at Sangamo Therapeutics, Inc., including Senior Vice President and Chief Technology Officer.ĭr. He has an accomplished track record of translating genome engineering technologies to product candidates as evidenced by leading ten therapeutic programs across ex vivo and in vivo therapies. Holmes has more than 20 years of experience working on the development and clinical translation of genome editing- and gene therapy-based approaches. Michael Holmes has joined Tessera Therapeutics as its Chief Scientific Officer to lead the development of novel technologies and transformative therapies. Michael Holmes, Ph.D., Chief Scientific Officerĭr. We’re thrilled that our research will be led by Mike Holmes, whose previous roles included spearheading development of the industry’s first gene editing platform and therapeutic candidates.” “To realize this goal, we’re building the field’s top team across all levels and functions of our organization. “We set out to revolutionize the field of genetic medicine by pioneering Gene Writing technology that can unlock the therapeutic potential of engineering DNA and address the short-comings of today’s gene therapy and gene editing approaches,” said Dr. “Their leadership, experiences, and mindsets will be critical in helping to realize our aspirations in genetic medicine, attract and maintain the best talent, and develop our pipeline of Gene Writer candidates to cure and prevent severe diseases.” Geoffrey von Maltzahn, CEO and Co-Founder of Tessera and General Partner, Flagship Pioneering. “Michael, Iain, and Bec are invaluable additions to our Tessera team and our mission to cure disease by writing in the code of life,” said Dr. In addition to the three executive appointments, Rebecca Wais, Ph.D., JD, Vice President, Intellectual Property and Legal Affairs, and Ian O’Reilly, Vice President, Head of GMP Quality, recently joined the Tessera team to bolster the company’s internal legal and manufacturing capabilities. Jacob Rubens, Ph.D., Co-Founder of Tessera and Senior Principal, Flagship Pioneering, has transitioned from Tessera’s Chief Scientific Officer to Chief Innovation Officer. CAMBRIDGE, Mass.-( BUSINESS WIRE)-Tessera Therapeutics, a biotechnology company pioneering a new approach in genetic medicine known as Gene Writing™ technology, today announced the expansion of its executive leadership team with appointments of Michael Holmes, Ph.D., Chief Scientific Officer, Iain McFadyen, Ph.D., Chief Data Officer, and Becky Lillie, Chief Human Resources Officer. Whenever you drop the tablet in its case and on the stand, it begins to charge and fires up Show Mode automatically.įinally, Amazon is making some changes to the Fire HD 8 Kids Edition. This comprises a case – which connects to the tablet’s micro-USB port and provides a couple of charging pins on the rear – and a simple hinged stand that can be connected to any USB power source. This feature first debuted in the US earlier this year and is designed to work alongside the new Show Mode Charging Dock, which you can buy in a bundle with the Fire HD 8. It shows the time, news, hints and tips on how to use Alexa, and adds visual aids to various Alexa queries, such as timers and questions about the weather. Next is Amazon’s “Show Mode”, a feature that fires up an onscreen display similar to what you see on the company’s Echo Show speaker. Alexa on the Fire HD 8 operates just like an Echo speaker does, including the ability to make calls and drop in on friends and family via their Echo speakers. First up, the Fire HD 8 receives hands-free Alexa support, allowing it to respond to the “Alexa” keyword without you having to touch the tablet. More interesting are the changes Amazon has made to its Fire OS software. Amazon Fire HD 8 (2018) review: Fire OS and Alexa This helps increase the quality of your weekly video calls to your Brexit-voting grandma in the Midlands. The rear 2-megapixel camera hasn’t changed, and quality is just as disappointing as before with washed-out colours and noisy images, but the front-facing camera has been upgraded to a 720p unit. One thing that does a better job is the new Fire HD 8’s camera capabilities. The version without them is £10 more expensive for both. Special offers are ads that automatically show on the screen when you turn on the tablet before unlocking it. Both are great value for money and nothing rivals them at this price for sheer usability.Īmazon continues to offer two further variants of the Fire HD 8: versions with and without “Special Offers”. Amazon Fire HD 8 (2018) review: Price and competitionĪt £80, the new 16GB Fire HD 8 remains the same price as the model it replaces, as does the 32GB model at £100. There are also a few tweaks to the Kids Edition of the tablet, notably a new interface and the addition of child-friendly audiobooks. The biggest change is that the Fire HD 8 now supports hands-free Alexa and “Show Mode”, which transforms the tablet into a cheaper version of Amazon’s Echo Show smart speaker. That’s it for new hardware: the rest is precisely as it was before. So what’s new? The front-facing camera is now 720p, up from 640 x 480, and the tablet’s microSD slot can take cards up to 400GB in capacity, rather than 256GB. READ NEXT: Our guide to the best tablets you can buy Amazon Fire HD 8 (2018) review: What you need to know That’s because it’s essentially the same tablet as the previous model, but that’s not necessarily a bad thing. The new Amazon Fire HD 8 is finally available and, if you were considering buying one with the hopes of a sizeable upgrade, it’s probably worth waiting a little longer. In 2018, that trend continued with a handful of small updates to Amazon’s middle-child tablet. It helps, too, that Amazon continues to improve the tablets year on year. £59.99 Buy now Amazon Fire HD 8 (2018) reviewĪmazon’s tablets may not be the last word in power or luxury, but they do the job for a low price, and make great gifts for kids. This is important because the dew point is dependent on relative humidity and temperature.Ībsolute humidity ranges, with the highest humidity at roughly 30 grams per cubic meter.Ībsolute Humidity is equivalent to the mass of the water vapor divided by the volume of the air and water vapor combination:Ībsolute humidity is affected by temperature or pressure changes, yet this is not accounted for in the formula. This represents the actual amount of water vapor present in a given quantity of air regardless of the temperature. It is worth exploring these measures to better understand dew point and how to measure it relative to temperature, and humidity.ĭew point is essentially the temperature at which air saturates to form vapor, this is equal to 100% relative humidity.Ībsolute Humidity is a measure of water vapor per cubic meter of air. Humidity Humidity is either measured in absolute terms, relative terms, or as specific humidity. Water vapor is a gas lighter than nitrogen or oxygen – the primary components of air. It is counter intuitive, since water is certainly heavier than air! But water in a gas form is not. So, when water vapor is in the air it displaces the air and lowers the overall molecular mass. The average molecular mass of air is around 29, and the molecular mass of water vapor is around 18. It is usually thought that air containing a higher humidity is denser than dry air, but this is not the case. Some areas are far drier than others, humidity can change depending on the time of day, and moisture in the air can be blown in or away by the wind. This can vary depending on various climate conditions. Humidity is also a measure of the amount of water vapor in the air. Of course, ice is water in its solid form. Similarly, changing states from water to ice is known as the frost point, as this is where frost would form. The temperature of the glass is colder than the air around the glass, and so, when the air, which contains water vapor makes contact with the glass, the vapor cools and begins to change state to become liquid. This happens because of a difference in relative temperature. Have you ever noticed your windows mist up on a freezing cold day? Or perhaps you have noticed droplets of water forming on the outside of an ice-cold glass? The higher the dew point, the more moisture there is in the air. Water vapor is the gaseous state of water or water in a gas form. The measure marks the point to which the air must be cooled to reach a saturation point, as water vapor in the air condenses to form dew. This is probably because it is the most accurate reflection of what weather conditions feel like, as it combines temperature and humidity.ĭew point is the atmospheric temperature at which dew can form. Dew point is growing in its use by meteorologists as a measure of humidity. Naturally, high-density panels blasting at users' eyes call for some disclaimers, and Apple apparently has those ready, too. As expected, Mac users can seamlessly transition their workspaces from their computers to their Vision Pro, extending slideshows, Safari browsers, and more into the augmented reality view. There are no proprietary controllers or additional hardware required to operate the machine.Īpple says the headset will field a pair of 4K Micro OLED displays for each eye and several external cameras for passthrough and hand tracking, besting the resolution quality and sensors of existing AR/VR headsets. The R1 chip is an especially important piece, working in tandem with the Vision Pro's external cameras and sensors for spatial rendering.Īlso: Apple Vision Pro: Price, features, release date, moreĪpple's Vision Pro headset relies solely on your eyes, fingers, and voice to work, from selecting elements on-screen by simply looking at them and pinching your index and thumb fingers to giving voice commands. Together, the headset offers floating interfaces of familiar apps and services like Safari, Disney Plus, FaceTime, iMessage, and more. Vision Pro will run on an all-new platform called visionOS via spatial computing, and is driven by an M2 and R1 chip. And, as multiple reports and sources familiar with the matter suggested, the headset's design does in fact resemble a pair of ski goggles (yay?), with Apple leaning more towards comfort and ease of use than performance and battery life. CloseĪpple's worst-kept secret, an AR headset by the name of Vision Pro, made its much-anticipated debut at WWDC this year. If you see inaccuracies in our content, please report the mistake via this form. If we have made an error or published misleading information, we will correct or clarify the article. Our editors thoroughly review and fact-check every article to ensure that our content meets the highest standards. Our goal is to deliver the most accurate information and the most knowledgeable advice possible in order to help you make smarter buying decisions on tech gear and a wide array of products and services. ZDNET's editorial team writes on behalf of you, our reader. Indeed, we follow strict guidelines that ensure our editorial content is never influenced by advertisers. Neither ZDNET nor the author are compensated for these independent reviews. This helps support our work, but does not affect what we cover or how, and it does not affect the price you pay. When you click through from our site to a retailer and buy a product or service, we may earn affiliate commissions. And we pore over customer reviews to find out what matters to real people who already own and use the products and services we’re assessing. We gather data from the best available sources, including vendor and retailer listings as well as other relevant and independent reviews sites. ZDNET's recommendations are based on many hours of testing, research, and comparison shopping. Works bi-directionally, which means that you won’t hear the noise coming from other call participants, and they won’t hear the noise coming from you. as well as any headsets, headphones, microphones and speakers. Supports almost all communication 600+ applications such as Skype, Zoom, Discord, Webex, QuickTime, Audacity, Loom, etc. Powerful noise reducing application that significantly reduces background noise during voice calls for both input and output audio devices.Ĭomes loaded with intelligent tools that work smoothly in real time without lags, so your calls will be uninterrupted and completely noiseless. The program works bi-directionally, which means that you won’t hear the noise coming from other call participants, and they won’t hear the noise coming from you. It is a comprehensive application that comes loaded with intelligent tools that work smoothly in real time without lags, so your calls will be uninterrupted and completely noiseless.It supports almost all communication 600+ applications such as Skype, Zoom, Discord, Webex, QuickTime, Audacity, Loom, etc. Krisp is a powerful yet simple-to-use noise reducing application that significantly reduces background noise during voice calls for both input and output audio devices. Free download Krisp 1.18.4 full version standalone offline installer for Windows PC, Krisp Overview swashbuckler fantasy series Pirates of the Caribbean, beginning in 2003. Nothing has been confirmed yet, and we are yet to know who will actually take the baton of Pirates. will turner elizabeth swann pirates of the caribbean willabeth potc edit love couple keira knightley orlando bloom movie movies film films cinema dead mans chest willabeth willturner elizabethswann orlandobloom keiraknightley piratesofthecaribbean potc. Keira Christina Knightley OBE is an English actress. Well, there were also some speculations after Johnny Depp had to take an exit for his trials that Pirates of the Caribbean might see a female lead starring Margot Robbie. According to a report in The Mirror, Keira Knightley - who played Elizabeth Swann in the first three Pirates films - has filmed a post-credits stinger for Dead. I think we’re gonna have a great screenplay, and we’re getting close.” That’s all I can tell you.” Sharing the next film’s update, “We’re all working on it. Keira Knightley Says Lusty ‘Pirates of the Caribbean’ Role Made Her Feel ‘Caged In’ and ‘Stuck’: I Wanted to ‘Break Out of That’. so I don’t really remember very much of it, but yes, it certainly was a very big year for me.”Ī few days back, Bruckheimer shared an update on the next instalment of Pirates of the Caribbean to ET and even revealed whether or not there will be Johnny Depp’s presence. That year was Bend It Like Beckham, Love Actually and Pirates of the Caribbean. Pirates of the Caribbean star and Chanel muse, Keira Knightley has a signature beauty look when shes off-screen. Elizabeth Turner (née Swann) is a fictional character in the Pirates of the Caribbean film series. So, it may just be time to get excited for what was already going to be one of the bigger movies of the year.Further talking about how big it was for her to be a part of a franchise like Pirates, Keira Knightley said, “It sort of launched me out of a rocket, really, as far as my career went. Pirates of the Caribbean star and Chanel muse, Keira Knightley has a signature beauty look when shes off-screen. It has been a decade since Keira Knightley, Orlando Bloom and Johnny Depp all appeared in a Pirates of the Caribbean film together. But that doesn't mean it will be any less sweet. Her appearance in the trailer is considerably brief, and it is likely, though this is just conjecture, that her role in the film will also be quite small. Well, not so fast!Ī recent international trailer for the fifth Pirates of the Caribbean film includes a shot of Knightley's Elizabeth Swann (now Turner), confirming that she will indeed be appearing in the film. Knightley, however, has in the past shot down any interest of returning for future installments, and her absence from Dead Men Tell No Tales' promotional material seemed to all but confirm that she would be sitting out a second straight film in the franchise. And this no doubt had fans hoping that Elizabeth Swann, played by Keira Knightley, would also reunite with Captain Jack Sparrow for another swashbuckling adventure. Knightley detailed her skyrocket to fame at age 17 when Pirates premiered in 2003 alongside Love. Margot Robbie is set to helm the films’ ship, taking the. 'She was the object of everybody's lust,' Knightley said of her ''Pirates' character in a cover story for the April issue of Harper's Bazaar UK released on Tuesday. We have known for some time that Pirates of the Caribbean: Dead Men Tell No Tales would feature the return of Orlando Bloom's Will Turner, one of the main characters from the original trilogy. It seems it almost wasn’t a Pirates life for Keira Knightley. Keira Knightley found the immediate Pirates of the Caribbean success to be a curse. Disney is planning on doing a Pirates of the Caribbean 6 film that will reportedly be female-centered but will not include Knightley. Keira Knightley reflected on her part as Elizabeth Swann in the 'Pirates of the Caribbean' franchise and said that she tried to avoid being cast in similar roles afterward. Our next After Effects template is this stunning mystical film opener from Envato Elements. Mystical Film Opener After Effects Template This whimsical premium After Effects template from Envato Elements features a fun hand-drawn writing effect and includes a full suite of letters and numbers as well as a wide range of symbols, and a bonus collection of arrows and scribbles to customize your design. Hand Drawn Alphabet After Effects Template Perfectly suited for sports montage, and cinematic video reels, this product is one of the best After Effects templates that will pay for itself many times over. 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Glitch Title Animations AE Particle Slideshow Intro & Openers Logo Templates Product Promo AE Titles Premium Dynamic Opener After Effects Template All products are shipped free of charge in the United States when you order over $500. You can securely purchase precious metals online, or you can call our customer service team at any time for assistance with an order. We offer many ways to purchase silver and gold bullion, depending on your needs. Scottsdale Mint is one of only a handful of private mints operating in the United States, and the gold and silver products it offers are created specifically for you. You may be able to find gold and silver from drop-shippers and secondhand dealers, but you can only find the finest-quality precious metals at the source. We are proud to be a family-owned company that understands your needs as an investor and strive to meet them in every way possible. 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Check out our article on syncing your tasks to Google Calendar to learn more. The benefit of doing this is so you can manage your schedule in a single place. Sync Copper Tasks to my Google CalendarĮach user can choose whether they want to sync tasks to their Google Calendar. Check out our article on the Gmail integration to learn more about this functionality. If you want to learn more about the four features mentioned on the 'Google Sync Settings' page, read on:Īs the box explains, signing up for Copper with a Gmail address automatically activates the Gmail sync. However, it's worth checking out our articles on the Google Suite Integrations to get the big picture, as these four settings are only part of it. By default, the option to Sync settings is turned on, but you can turn it off completely or turn it off selectively for each setting. Moreover, the application is available in 7 languages (English, French, German, Spanish, Italian, Japanese and Chinese).The 'Google Sync Settings' page covers four aspects of our integration with various Google apps, two of which are settings you can adjust. In Windows 10, go to Settings > Accounts > Sync your settings. This version has been optimized for macOS High Sierra and later. In this way, you can contact us for any suggestions and improvements in a few clicks. Feedbacks can be sent directly from the application. If you need more features or if the application does not sync some of your apps, we are here to help you. You can specify your own files, and it will back up and sync them seamlessly. Moreover, the app is not limited to preferences files. It allows you to write notes about what to do. This is not a standalone app In order to use this app, you need an application that uses the. We know that many users use SyncSettings to set up new computers or new versions of macOS. Create Locale/Tasker actions to apply specific sync settings. Your favorite tools are already integrated: Adobe Photoshop, Adobe Lightroom, Adobe Illustrator, Atom, IntellijIdea, Omnigraffle, PHP Storm, P圜harm, Tower 3, Transmit, WebStorm, Xcode, Bash, Bundler, Git, Docker, Emacs, Heroku, Maven, MySQL, Perl, PostgreSQL, Vim, Zsh and much more. We thought about developers and designers. Besides, the application supports a list of more than 400 non-standard applications and executables. It gives you an overview of the password sync configuration. SyncSettings already supports almost all the applications of the Mac App Store. Run the script in the Get the status of password sync settings section. The project has been under construction for several months to support the largest number of apps. Contribute Financial Contributions Top financial contributors. All cloud providers are compatible such as iCloud, Google Drive, One Drive, and even GitHub. Sync Settings will help you to keep your sublime settings synced among multiple devices. In this way, all your computers will always have access to the same data. So, you can then keep your data locally or store them in the cloud. SyncSettings packages your preferences into a single ssbackup file. Tired of settling all your apps after a new macOS install or manually keeping the same settings across several macs? SyncSettings will do it for you. SyncSettings is the first application able to back up and sync the preferences of your Mac apps. |
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